Prism: Home

Where hope, science & understanding meet.

From the aspirin on the shelves of your local drugstore, to the insulin prescribed by a doctor, to the pacemaker keeping someone’s heart on track – all have been subject to clinical trials, and integral part of the Food and Drug Administration (FDA) approval process.

A critical step in an important process

Drugs and medical devices undergo years of laboratory testing before they reach the clinical trial phase. Researchers must acquire approval from the FDA for approval to continue research and testing in humans. Clinical trials are essential to measure the efficacy and safety of drugs before they are available for widespread use.

Changing lives, every day.

The impact of clinical trials are seen in our everyday lives, in the confidence with which we can take over-the-counter drugs – or in the life-saving benefits of a breakthrough medication for a victim of Leukemia.

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Public Health and Safety

Prior to the development of the FDA’s rigorous and highly regulated method, consumers had to rely upon the anecdotal observation of physicians or spurious claims of pharmacists. In 1906, in order to protect public health and safety, the fledgling FDA passed the first regulatory drug act – the Pure Food and Drug Act.

In 1938, the enactment of the U.S. Food, Drug, and Cosmetic Act subjected new drugs to pre-market safety evaluation for the first time, thus enabling FDA regulators to review both pre-clinical and clinical test results, giving them the authority to block the marketing of a new drug formally or delay it by requiring additional data.

Alongside the evolving standards of drug regulations, closer regulation of the clinical trial process. The resulting process today is designed to protect the safety of study participants, promote the development of lifesaving drugs, and keep public health and safety at the center of medical advancement. In the century since the first drug act, the research and medical community in cooperation with the FDA, have developed the foremost institutional authority for conducting and evaluating controlled clinical drug trials.

Doing the right thing

Know that you’ve done your part to help make important medications available to those who need them. If you have a friend or family member who relies on a medication to treat a chronic disease or illness, they have benefited from the work of a clinical trial, and a volunteer like you who gave their time and effort to aid in the approval process.

Fair compensation for your time

You’ll be compensated based on the time you spend as a study participant.

Medical exam & monitoring

As a study participant, you’ll likely receive a full medical examination and testing for a variety of conditions. In some cases volunteers might have access to treatments or medicines before they are available to the general population.

Understanding
Clinical Research
Public Health
and Safety
Why
Volunteer?
Prism Clinical Research
1000 Westgate Dr, Suite 149, St. Paul, MN 55114
Phone: 651-641-2900

Changing lives, advancing science, furthering the reach of medicine.

Prism Clinical Research provides, FDA approved, investigational pharmaceutical and medical device testing services on behalf of drug and device manufacturers, academic and private physicians as well as other researchers across Minnesota.

At Prism, we are committed to the advancement of medical knowledge and the health of our community. We have been conducting Phase I clinical trials since 2005, helping many important drugs reach FDA approval. Prism is a locally owned and operated, independent facility in the heart of the Minneapolis/St. Paul metropolitan area.

Whether you are here because you are interested in participating in a clinical trial, or you’re searching for a trusted partner to conduct a study on your behalf, our hope is that you find the information you need and the confidence to take the next step.

With your help, we can make a difference.

Learn what Prism Volunteers are saying:

"I am VERY pleased with Prism Research. I enjoy the studies and the staff is always friendly and they all make you feel as comfortable as possible. The study compensation program is very good as well! Thank you."

“Concerned enough to ask questions. I enjoy visiting with the staff. I look forward to future studies and may qualify to participate in.”

“Overall you do a great job! Your staff is very friendly and accommodating. Your facility is very comfortable. Thanks!”

“Staff was courteous and well informed of the nature of the study and all of the requirements that went with it.”

“Overall my experiences at Prism have been very positive and directly linked to the Staff - their demeanor, humor and professional approach.”

Males	Males are allowed to participate
Females	Females are allowed to participate.
Age	Type 1 Diabetes: Ages 21-80 Type 2 Diabetes: Ages 30-80
Body Mass Index (BMI)	Less than or equal to 45 kg/m²
Weight	No weight requirements
Tobacco/Nicotine Use	Tobacco use is prohibited while at clinic. Use of tobacco at other times is allowed
Alcohol/Drug Abuse History	History of drug/alcohol abuse will be considered on a case by case basis.
Health History	Excluded: History of or currently requiring dialysis History of kidney or other organ transplantation Other exclusions related to health history may apply. Prism staff will review participants’ health history to determine eligibility.
Medications	Excluded: Ongoing treatment of systemic immunosuppression therapy Other medications exclusions may apply, however; stable use of many medications is allowed. Prism staff will review participants’ medication lists to determine eligibility.

Inpatient Stays	There are no overnight stays during this study
Outpatient Visits	Following the two part screen, there are 16 outpatient visits over the course of approximately 54 weeks. Three outpatient visits will last between 3-4 hours. The remaining 13 outpatient visits will last approximately 45 minutes

Males	Males 60 years or older are allowed to participate
Non-Pregnant Females	Non-pregnant women 60 years or older are allowed to participate
Pregnant Females	Pregnant females 18 years or older are allowed to participate
Body Mass Index (BMI)	No weight or BMI requirements
Tobacco/Nicotine Use	No tobacco use when at research unit.
Drug Testing	Must test negative for drugs of abuse.
Health History	Must be generally healthy with no personal or family history of thyroid diseases or conditions.
Restricted Medications	No use of prescription medications, aspirin, or Unisom use in the 30 days before the blood draw.
Allowed Medications	Use of prenatal vitamins are allowed. Use of non-prescription medications, vitamins, or supplements not listed here will be considered on a case by case basis.

Males	Men are allowed to participate
Females	Women are allowed to participate
Age	18-65 years
Weight	Must weigh between 132-198 pounds
Health History	Must be healthy; not being evaluated or treated for any medical conditions unless otherwise approved on a case by case basis by the study doctor

Males	Males are allowed to participate
Females	Females are allowed to participate.
Age	Type 1 Diabetes: Ages 21-80 Type 2 Diabetes: Ages 30-80
Body Mass Index (BMI)	Less than or equal to 45 kg/m²
Weight	No weight requirements
Tobacco/Nicotine Use	Tobacco use is prohibited while at clinic. Use of tobacco at other times is allowed
Alcohol/Drug Abuse History	History of drug/alcohol abuse will be considered on a case by case basis.
Health History	Excluded: History of or currently requiring dialysis History of kidney or other organ transplantation Other exclusions related to health history may apply. Prism staff will review participants’ health history to determine eligibility.
Medications	Excluded: Ongoing treatment of systemic immunosuppression therapy Other medications exclusions may apply, however; stable use of many medications is allowed. Prism staff will review participants’ medication lists to determine eligibility.

Prism Clinical Research

Studies for Particpants Diagnosed with Type 2 Diabetes

Register with Our Database

Study 1419: Participants with Type 1 or Type 2 Diabetes

Study 1505: Healthy Pregnant Females 18 or Older and Healthy Males and Females Ages 60 and Older

Study 1503: Male and Female Participants