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  • Studies for Particpants Diagnosed with Type 2 Diabetes

    Throughout 2015, Prism will be conducting several studies for participants diagnosed with type 2 diabetes.  These studies will be posted on our website once recuritment is officially underway.  

    Don't see a study listed?  Maybe a study is posted but it's not a match for you?  That's ok, we still want to hear from you!  Each study will have an unique set of qualifications.  Register with our database now so we can identify the right study for you as soon as it becomes availble.

    The information you provide is only used to help us determine your eligibility for current and future studies. We will not share or sell this info with any third party. 

    Thanks for your interest, you'll find the intake form here

  • Register with Our Database

    Get started on the volunteer process by registering your basic information with our database. This information is provided to help us determine your eligibility for current and future studies. We will not share or sell this info with any third party. 

    Thanks for your interest, you'll find the intake form here

  • Study 1418: Healthy Male and Female Particpants

    Research Purpose: Study 1418 is designed to evaluate an investigational drug being developed for the treatment of influenza. Participants will receive twice daily, oral doses of the investigational drug or a placebo.  The following will be evaluated:

    • How quickly the body process and eliminates the investigational drug
    • The general safety/tolerability of the investigational drug
    • The male reproductive safety of the investigational drug  

    Minimum Screening Qualifications:


    Men are allowed to participate; males who have a vasectomy cannot participate.


    Women are allowed to participate


    18-65 years

    Body Mass Index (BMI)

    Greater than or equal to 16 kg/m²


    Greater than or equal to 96.8 pounds

    Tobacco/Nicotine Use

    No tobacco/nicotine use in the 3 months prior to the start of the study until study completion of the study

    Drug Testing

    Must test negative for drugs of abuse. 

    Alcohol/Drug Abuse History

    No history of drug or alcohol abuse within 2 years before the screening appointment.

    Health History

    Must be healthy; not being evaluated or treated for any medical conditions unless otherwise approved on a case by case basis by the study doctor

    Restricted Medications

    No required regular use of any prescription medications, non-prescription medications, vitamins, or herbal supplements not listed below

    Allowed Medications

    Prescribed/stable hormonal birth control is allowed


    Study Time Commitment: For participants who qualify based on screening evaluation, study participation will last for approximately 7 weeks.

    Inpatient Stays

    • Participants will admit for an inpatient stay at Prism Clinical Research 1 time.
    • The inpatient stay will last approximately 1 and a half weeks (11 overnights)

    Outpatient Visits

    • There is one outpatient visit and one follow-up phone call.
    • The outpatient visit will last between approximately 2 hours
    • MALES ONLY: based on laboratory results, some males may be required to return for 1-3 additional outpatient visits.  For these participants, the study time commitment may be as long as 16 weeks. Additional compensation will be provided for completion of these visits.


    Compensation: Up to $2,975.00




    V1 AD 21Nov14


  • Study 1419: Participants with Type 1 or Type 2 Diabetes

    Research Purpose: Study 1419 is designed to evaluate an investigational injected medication being developed for the treatment of diabetic kidney disease in participants with either type 1 or type 2 diabetes and various degrees of kidney damage. 

    Minimum Screening Qualifications:


    Males are allowed to participate


    Females are allowed to participate.


    • Type 1 Diabetes: Ages 21-80
    • Type 2 Diabetes: Ages 30-80

    Body Mass Index (BMI)

    Less than or equal to 45 kg/m²


    No weight requirements

    Tobacco/Nicotine Use

    Tobacco use is prohibited while at clinic.  Use of tobacco at other times is allowed

    Alcohol/Drug Abuse History

    History of drug/alcohol abuse will be considered on a case by case basis.

    Health History


    • History of or currently requiring dialysis
    • History of kidney or other organ transplantation

    Other exclusions related to health history may apply. Prism staff will review participants’ health history to determine eligibility.



    • Ongoing treatment of systemic immunosuppression therapy

    Other medications exclusions may apply, however; stable use of many medications is allowed.  Prism staff will review participants’ medication lists to determine eligibility.


    Study Time Commitment: For participants who qualify based on screening evaluations, study participation will last for approximately 1 year.

    Inpatient Stays

    • There are no overnight stays during this study

    Outpatient Visits

    • Following the two part screen, there are 16 outpatient visits over the course of approximately 54 weeks.
    • Three outpatient visits will last between 3-4 hours.  The remaining 13 outpatient visits will last approximately 45 minutes


    Compensation for study participation time: Up to $1,450.00.




    V1 09FEB2015  1419VPI


Where hope, science & understanding meet.

From the aspirin on the shelves of your local drugstore, to the insulin prescribed by a doctor, to the pacemaker keeping someone’s heart on track – all have been subject to clinical trials, and integral part of the Food and Drug Administration (FDA) approval process.

A critical step in an important process

Drugs and medical devices undergo years of laboratory testing before they reach the clinical trial phase. Researchers must acquire approval from the FDA for approval to continue research and testing in humans. Clinical trials are essential to measure the efficacy and safety of drugs before they are available for widespread use.

Changing lives, every day.

The impact of clinical trials are seen in our everyday lives, in the confidence with which we can take over-the-counter drugs – or in the life-saving benefits of a breakthrough medication for a victim of Leukemia.

Public Health and Safety

Prior to the development of the FDA’s rigorous and highly regulated method, consumers had to rely upon the anecdotal observation of physicians or spurious claims of pharmacists. In 1906, in order to protect public health and safety, the fledgling FDA passed the first regulatory drug act – the Pure Food and Drug Act.

In 1938, the enactment of the U.S. Food, Drug, and Cosmetic Act subjected new drugs to pre-market safety evaluation for the first time, thus enabling FDA regulators to review both pre-clinical and clinical test results, giving them the authority to block the marketing of a new drug formally or delay it by requiring additional data.

Alongside the evolving standards of drug regulations, closer regulation of the clinical trial process. The resulting process today is designed to protect the safety of study participants, promote the development of lifesaving drugs, and keep public health and safety at the center of medical advancement. In the century since the first drug act, the research and medical community in cooperation with the FDA, have developed the foremost institutional authority for conducting and evaluating controlled clinical drug trials.

Doing the right thing

Know that you’ve done your part to help make important medications available to those who need them. If you have a friend or family member who relies on a medication to treat a chronic disease or illness, they have benefited from the work of a clinical trial, and a volunteer like you who gave their time and effort to aid in the approval process.

Fair compensation for your time

You’ll be compensated based on the time you spend as a study participant.

Medical exam & monitoring

As a study participant, you’ll likely receive a full medical examination and testing for a variety of conditions. In some cases volunteers might have access to treatments or medicines before they are available to the general population.

Changing lives, advancing science, furthering the reach of medicine.

Prism Clinical Research provides, FDA approved, investigational pharmaceutical and medical device testing services on behalf of drug and device manufacturers, academic and private physicians as well as other researchers across Minnesota.

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At Prism, we are committed to the advancement of medical knowledge and the health of our community. We have been conducting Phase I clinical trials since 2005, helping many important drugs reach FDA approval. Prism is a locally owned and operated, independent facility in the heart of the Minneapolis/St. Paul metropolitan area. 

Whether you are here because you are interested in participating in a clinical trial, or you’re searching for a trusted partner to conduct a study on your behalf, our hope is that you find the information you need and the confidence to take the next step. 

With your help, we can make a difference.

Learn what Prism Volunteers are saying:

Volunteer Large 13

"I am VERY pleased with Prism Research. I enjoy the studies and the staff is always friendly and they all make you feel as comfortable as possible. The study compensation program is very good as well! Thank you."

  • Volunteers 08

    “Concerned enough to ask questions. I enjoy visiting with the staff. I look forward to future studies and may qualify to participate in.”

  • Volunteers 05

    “Overall you do a great job! Your staff is very friendly and accommodating. Your facility is very comfortable. Thanks!”

  • Volunteers 06

    “Staff was courteous and well informed of the nature of the study and all of the requirements that went with it.”

  • Volunteers 07

     “Overall my experiences at Prism have been very positive and directly linked to the Staff - their demeanor, humor and professional approach.”

Please provide us with your contact information (below) and will get back to you as soon as possible.

If you have a general question, check Volunteer FAQ for an answer. If you're unsure of who to contact, please visit the Contact Us page.